RAD-140 10mg (Testolone)

The "Testosterone" of SARMs

RAD-140 (Testolone) is widely considered the strongest SARM available for pure muscle building. It was designed to replace Testosterone Replacement Therapy (TRT) and mimics the anabolic effects of testosterone without the androgenic side effects.

It provides rapid increases in strength, size, and vascularity. It is dry (no water retention) and adds a hard, grainy look to the physique.

Key Benefits:

• Mass & Strength: Comparable to a mild steroid cycle (like Anavar or low-dose Test).
• Neuroprotective: Protects brain cells from neurodegeneration.
• Fat Loss: Increases metabolic rate and promotes lipolysis.
• Vascularity: Increases blood flow and muscle pumps.

Dosage:

• Standard: 10mg - 20mg per day.
• Half-Life: 60 hours (Very long). Can be dosed once every other day or daily.

1. Description — Clinical summary

RAD-140 (Testolone) is a potent, orally bioavailable, non-steroidal selective androgen receptor modulator (SARM). It is being studied for the treatment of muscle wasting and breast cancer. It has a high affinity for the androgen receptor (Ki = 7 nM).

Key features:

• Active compound: RAD-140.
• Class: SARM.
• Anabolic Ratio: 90:1 (vs Testosterone 100:100).
• Primary Use: Bulking, Strength, Recomp.

2. Benefit & Effects

• Muscle Growth: Rapidly builds lean muscle tissue.
• Strength: Significant strength gains within the first week.
• Bone Density: Increases bone mineral density.
• Brain Health: Unique neuroprotective properties against Alzheimer's and neurotoxins.

3. How does it work? (Mechanism of action)

Mechanism of action — pharmacology summary:

• Selective Binding: Binds strictly to androgen receptors in muscle and bone tissue.
• Sparing Prostate: Has very little effect on the prostate or other androgen-sensitive organs (unlike steroids).
• No Aromatization: Does not convert to estrogen.

4. Dosage — usage guidelines

Dosage:

• Beginner: 10mg per day.
• Advanced: 20mg per day. Do not exceed 30mg due to diminishing returns.

Administration:

• Frequency: Once daily is fine due to long half-life.
• Cycle Length: 8-10 weeks.

Stacking:

• Bulking: LGD-4033 + MK-677.
• Cutting: Cardarine (GW-501516) + Ostarine.

5. Side effects

Common:

• Suppression: It is suppressive to natural testosterone (though less than steroids). PCT is recommended.
• Aggression: Increased irritability/aggression in some users.
• Hair Shedding: Some shedding reported (temporary telogen effluvium).

Rare/Serious:

• Liver: While safer than oral steroids, elevated liver enzymes can occur. Use liver support (NAC/TUDCA).

6. Storage

• Store at room temperature.
• Protect from light.